- Fourth-year quarterback enters his fourth season with the Chiefs in 2020.
- Threw 26 touchdown passes and 2,810 yards through Week 8 of the 2018 season, the most passing touchdowns and passing yards in a player's first nine career games in the Super Bowl era.
- Threw 29 touchdown passes in his first 10 career NFL games, more TD throws than any QB in NFL history in their first 10 games.
- Recorded longest touchdown pass of his career (89 yards) in Week 17 vs. Oakland (12/30/18).
- Made his NFL debut and first start during the Chiefs 2017 regular season finale against the Broncos (12/31) and completed 22 of 35 passes (62.9%) for 284 yards. His 284 passing yards are the second-most by a rookie passer in a single-game in franchise history. He added seven carries for 10 yards.
- Originally entered the NFL as the 10th overall pick in the first round of the 2017 NFL Draft by Kansas City.
- The Chiefs traded traded the No. 27 overall pick, a third-round pick and their 2018 first-round selection to the Buffalo Bills in order to move up to the No. 10 spot where they selected Mahomes
- During the 2018 season became just the second quarterback (QB Peyton Manning in 2013) in NFL history to throw for 50 touchdowns and 5,000 passing yards in a single-season.
- Became the fastest player to 4,000 passing yards by accomplishing the feat in just 13 career games.
- Broke the Chiefs single-season passing touchdown record, passing Len Dawson with 31 touchdown passes through Week 10 of the 2018 season.
- Recorded six touchdown passes against the Steelers (9/16/18), tying Chiefs QB Len Dawson for most touchdown passes in one game in team history.
- First quarterback in Chiefs history to throw for 300+ yards in eight consecutive games.
- Named AFC Offensive Player of Month for September after starting the 2019 season with the league-lead in touchdown passes (10) and 1,510 passing yards, the third-most in NFL history through four games.
- Named AFC Offensive Player of Week following Week 2 of the 2019 season, where he threw four touchdowns, completed 30-of-44 passes for 443 yards against the Oakland Raiders, marking his second-highest yardage total in a single game.
- Awarded National Football League's Most Valuable Player for 2018 season.
- Won the ESPY for the Best NFL Player in ESPN's annual awards show in July of 2019.
- Named 2018 FedEx Air Player of the year.
- Three-Time Fedex Air Player of the Week in 2018 season (Weeks 2, 7 and 8).
- Earned back-to-back AFC Offensive Player of the Week honors after his debut against the Chargers (9/9) where he completed 15 of 27 passes (55.5%) for 256 yards and four touchdowns and in Week 2 against the Steelers (9/16), completing 26 of 28 passes for 326 yards and six touchdowns.
- 2018 AFC Player of the Month for September.
- 2019 Pro Bowl Selection.
- Originally entered the NFL as a first-round pick (10th overall) by the Kansas City Chiefs in the 2017 NFL Draft.
|1||Texans||W 34 - 20||24||32||211||6.6||3||0||1||8||123.3|
|2017||Kansas City Chiefs||1||1||22||35||284||8.1||0||1||2||15||76.4||7||10||1.4||0|
|2018||Kansas City Chiefs||16||16||383||580||5097||8.8||50||12||26||171||113.8||60||272||4.5||2||9||2|
|2019||Kansas City Chiefs||14||14||319||484||4031||8.3||26||5||17||127||105.3||43||218||5.1||2||3||2|
|2020||Kansas City Chiefs||1||1||24||32||211||6.6||3||0||1||8||123.3|